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Boron affects calcium metabolism, and a link between boron deficiency and arthritis has been suggested.1 Although people with osteoarthritis have been reported to have lower stores of boron in their bones than people without the disease, other minerals also are deficient in the bones of people with osteoarthritis.2 One double-blind trial found that 6 mg of boron per day, taken for two months, relieved symptoms of osteoarthritis in five of ten people, compared with improvement in only one of the ten people assigned to placebo.3This promising finding needs confirmation from larger trials.
1. Newnham RE. The role of boron in human nutrition. J Applied Nutr 1994;46:81-5.
2. Helliwell TR, Kelly SA, Walsh HP, et al. Elemental analysis of femoral bone from patients with fractured neck of femur or osteoarthrosis. Bone 1996;18:151-7.
3. Travers RL, Rennie GC, Newnham RE. Boron and arthritis: the results of a double-blind pilot study. J Nutr Med 1990;1:127-32.
Boron supplementation at 3–9 mg per day may be beneficial, particularly in treating people with juvenile RA, according to very preliminary research.1 The benefit of using boron to treat people with RA remains unproven.
Boron supplementation has been reported to reduce urinary loss of calcium and magnesium in some,1 but not all,2 preliminary research. However, those who are already supplementing with magnesium appear to achieve no additional calcium-sparing benefit when boron is added.3 Finally, in the original report claiming that boron reduced loss of calcium,4 the effect was achieved by significantly increasing estrogen and testosterone levels, hormones that have been linked to cancer risks. Therefore, it makes sense for people with osteoporosis to supplement with magnesium instead of, rather than in addition to, boron.
One trial studying postmenopausal women combined hormone replacement therapy with magnesium (600 mg per day), calcium (500 mg per day), vitamin C, B vitamins, vitamin D, zinc, copper, manganese, boron, and other nutrients for an eight- to nine-month period.5 In addition, participants were told to avoid processed foods, limit protein intake, emphasize vegetable over animal protein, and limit consumption of salt, sugar, alcohol, coffee, tea, chocolate, and tobacco. Bone density increased a remarkable 11%, compared to only 0.7% in women receiving hormone replacement alone.
1. Nielsen FH, Hunt CD, Mullen LM, Hunt JR. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women. FASEB J 1987;1:394-7.
2. Meacham SL, Taper LJ, Volpe SL. Effect of boron supplementation on blood and urinary calcium, magnesium, and phosphorus, and urinary boron in athletic and sedentary women. Am J Clin Nutr 1995;61:341-5.
3. Hunt CD, Herbel JL, Nielsen FH. Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations. Am J Clin Nutr 1997;65:803-13.
4. Nielsen FH, Hunt CD, Mullen LM, Hunt JR. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women. FASEB J 1987;1:394-7.
5. Abraham GE, Grewal H. A total dietary program emphasizing magnesium instead of calcium. J Reprod Med 1990;35:503-7.
Boron is a nonmetallic element present in the diet and in the human body in trace amounts. Whether boron is an essential nutrient for humans remains in debate.
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The information presented by Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2017.
| Supplement Facts |
Serving Size: 1 Capsule
Servings Per Container: 120
|Amount Per Serving||(2 Capsules)||%DV||(4 Capsules)||%DV|
|Copper (as Copper Gluconate)||250 mcg||25.000%||500 mg||25.000%|
|Vitamin D (as Cholecalciferol Prep.)||200 IU||100.000%||400 IU||100.000%|
|Calcium (as Calcium Carbonate, Calcium Citrate and Dicalcium Phosphate)||500 mg||100.000%||1000 mg||100.000%|
|Magnesium (as Magnesium Oxide & Taurinate)||250 mg||125.000%||500 mg||125.000%|
|Manganese (as manganese gluconate)||2.5 mg||250.000%||5 mg||250.000%|
|Zinc (as zinc picolinate)||7.5 mg||100.000%||15 mg||100.000%|
|Boron (as Boron Citrate)||1.5 mg||**||3 mg||**|
**Daily Value (DV) not established.
Ingredients: Potato Starch, Gelatin, Starch, Croscarmellose Sodium, Purifeid Water, Lecithin, Magnesium Stearate, MCT.