Twinlab Chelated Manganese 10mg (100 caps)

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Twinlab Manganese is a natural chelated formula that plays a role in the formation of bone, cartilage, and skin. Each capsule delivers 10 mg of elemental manganese from chelated manganese gluconate.
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  • Soothes female discomfort during midlife changes
  • Plays a key role in energy production and aids normal bone growth
  • Each capsule contains 10 mg of chelated manganese
Twinlab Manganese is a natural chelated formula that plays a role in the formation of bone, cartilage, and skin. Each capsule delivers 10 mg of elemental manganese from chelated manganese gluconate.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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Health Notes

Disclaimer: The following content is provided by Aisle7 and is for informational purposes only. It is based on scientific studies, clinical experience, or usage as cited in each article. Hi-Health provides this information as a service but does not endorse it. In addition, Aisle7 does not recommend or endorse any specific products.

Manganese

Manganese
This nutrient has been used in connection with the following health goals
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Type 2 Diabetes
Dose: Refer to label instructions
People with diabetes may have low manganese levels, which can contribute to glucose intolerance. Supplementing with the mineral may help. (more)
Hypoglycemia
Dose: Refer to label instructions
Manganese helps control blood sugar levels in people with diabetes, and since there are similarities in the way the body regulates high and low blood sugar levels, it might be helpful for hypoglycemia as well. (more)
Type 1 Diabetes
Dose: Refer to label instructions
People with diabetes may have low manganese levels, which can contribute to glucose intolerance. Supplementing with the mineral may help. (more)
Sprains and Strains
Dose: Refer to label instructions
Trace minerals, such as manganese, are known to be important in the biochemistry of tissue healing. (more)
Osteoporosis
Dose: Refer to label instructions
A combination of minerals including manganese was reported to halt bone loss in one study. Some doctors recommend manganese to people concerned with bone mass maintenance. (more)
Osgood-Schlatter Disease
Dose: Refer to label instructions
Some doctors have reported good results using a combination of zinc, manganese, and vitamin B6 for people with Osgood-Schlatter disease. (more)
Type 2 Diabetes
Dose: Refer to label instructions People with diabetes may have low blood levels of manganese.1 Animal research suggests that manganese deficiency can contribute to glucose intolerance and may be reversed by supplementation.2 A young adult with insulin-dependent diabetes who received oral manganese chloride (3 to 5 mg per day as manganese chloride) reportedly experienced a significant fall in blood glucose, sometimes to dangerously low levels. In four other cases, manganese supplementation had no effect on blood glucose levels.3 People with diabetes wishing to supplement with manganese should do so only with a doctor’s supervision.
References

1. Kosenko LG. Concentration of trace elements in the blood of patients with diabetes mellitus. Fed Proc Transl (Suppl) 1965;24:237-8.

2. Baly DL, Schneiderman JS, Garcia-Welsh AL. Effect of manganese deficiency on insulin binding, glucose transport and metabolism in rat adipocytes. J Nutr 1990;120:1075-9.

3. Rubenstein AH, Levin NW, Elliott GA. Hypoglycaemia induced by manganese. Nature (London) 1962;194:188-9.

Hypoglycemia
Dose: Refer to label instructions   

Research has shown that supplementing with chromium (200 mcg per day)1 or magnesium (340 mg per day)2 can prevent blood sugar levels from falling excessively in people with hypoglycemia. Niacinamide (vitamin B3) has also been found to be helpful for hypoglycemic people.3 Other nutrients, including vitamin C, vitamin E, zinc, copper, manganese, and vitamin B6, may help control blood sugar levels in diabetics.4 Since there are similarities in the way the body regulates high and low blood sugar levels, these nutrients might be helpful for hypoglycemia as well, although the amounts needed for that purpose are not known.

References

1. Anderson RA et al. Chromium supplementation of humans with hypoglycemia. Fed Proc 1984;43:471.

2. Stebbing JB et al. Reactive hypoglycemia and magnesium. Magnesium Bull 1982;2:131-4.

3. Shansky A. Vitamin B3 in the alleviation of hypoglycemia. Drug Cosm Ind 1981;129(4):68-69,104-5.

4. Gaby AR, Wright JV. Nutritional regulation of blood glucose. J Advancement Med 1991;4:57-71.

Type 1 Diabetes
Dose: Refer to label instructions People with diabetes may have low blood levels of manganese.1 Animal research suggests that manganese deficiency can contribute to glucose intolerance and may be reversed by supplementation.2 A young adult with insulin-dependent diabetes who received oral manganese (3 to 5 mg per day as manganese chloride) reportedly experienced a significant fall in blood glucose, sometimes to dangerously low levels. In three other people with type 1 diabetes, manganese supplementation had no effect on blood glucose levels.3 People with type 1 diabetes wishing to supplement with manganese should do so only with a doctor’s close supervision.
References

1. Kosenko LG. Concentration of trace elements in the blood of patients with diabetes mellitus. Fed Proc Transl (Suppl) 1965;24:237-8.

2. Baly DL, Schneiderman JS, Garcia-Welsh AL. Effect of manganese deficiency on insulin binding, glucose transport and metabolism in rat adipocytes. J Nutr 1990;120:1075-9.

3. Rubenstein AH, Levin NW, Elliott GA. Hypoglycaemia induced by manganese. Nature (London) 1962;194:188-9.

Sprains and Strains
Dose: Refer to label instructions   

Zinc is a component of many enzymes, including some that are needed to repair wounds. Even a mild deficiency of zinc can interfere with optimal recovery from everyday tissue damage as well as from more serious trauma.1 Trace minerals, such as manganese, copper, and silicon are also known to be important in the biochemistry of tissue healing.2, 3, 4, 5 However, there have been no controlled studies of people with sprains or strains to explore the effect of deficiency of these minerals, or of oral supplementation, on the rate of healing.

References

1. Sandstead HH. Understanding zinc: Recent observations and interpretations. J Lab Clin Med 1994;124:322-7.

2. Tenaud I, Sainte-Marie I, Jumbou O, et al. In vitro modulation of keratinocyte wound healing integrins by zinc, copper and manganese. Br J Dermatol 1999;140:26-34.

3. Pereira CE, Felcman J. Correlation between five minerals and the healing effect of Brazilian medicinal plants. Biol Trace Elem Res 1998;65:251-9.

4. Carlisle EM. Silicon as an essential trace element in animal nutrition. Ciba Found Symp 1986;121:123-39.

5. Leach RM. Role of manganese in mucopolysaccharide metabolism. Fed Proc 1971;30:991.

Osteoporosis
Dose: Refer to label instructions

Interest in the effect of manganese and bone health began when famed basketball player Bill Walton’s repeated fractures were halted with manganese supplementation.1 A subsequent, unpublished study reported manganese deficiency in a small group of osteoporotic women.2 Since then, a combination of minerals including manganese was reported to halt bone loss.3 However, no human trial has investigated the effect of manganese supplementation alone on bone mass. Nonetheless, some doctors recommend 10 to 20 mg of manganese per day to people concerned with maintenance of bone mass.

One trial studying postmenopausal women combined hormone replacement therapy with magnesium (600 mg per day), calcium (500 mg per day), vitamin C, B vitamins, vitamin D, zinc, copper, manganese, boron, and other nutrients for an eight- to nine-month period.4 In addition, participants were told to avoid processed foods, limit protein intake, emphasize vegetable over animal protein, and limit consumption of salt, sugar, alcohol, coffee, tea, chocolate, and tobacco. Bone density increased a remarkable 11%, compared to only 0.7% in women receiving hormone replacement alone.

References

1. Gold M. Basketball bones. Science 1980;80:101-2.

2. Raloff J. Reasons for boning up on manganese. Science News 1986;Sep 27:199 [review].

3. Strause L, Saltman P, Smith KT, et al. Spinal bone loss in postmenopausal women supplemented with calcium and trace minerals. J Nutr 1994;124:1060-4.

4. Abraham GE, Grewal H. A total dietary program emphasizing magnesium instead of calcium. J Reprod Med 1990;35:503-7.

Osgood-Schlatter Disease
Dose: Refer to label instructions  

Another group of doctors has reported good results using a combination of zinc, manganese, and vitamin B6 for people with Osgood-Schlatter disease; however, the amounts of these supplements were not mentioned in the report.1 Most physicians would consider reasonable daily amounts of these nutrients for adolescents to be 15 mg of zinc, 5 to 10 mg of manganese, and 25 mg of vitamin B6. Larger amounts might be used with medical supervision.

References

1. Aston B. Manganese and man. J Orthomolec Psychiatry 1980;9:237-49.

Manganese is an essential trace mineral needed for healthy skin, bone, and cartilage formation, as well as glucose tolerance. It also helps activate superoxide dismutase (SOD)—an important antioxidant enzyme.

Copyright © 2018 Healthnotes, Inc. All rights reserved. www.healthnotes.com

Learn more about Healthnotes, the company.

The information presented by Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2018.

Supplemental Facts

Ingredients

Supplement Facts

Serving Size 1 Capsule

 Amount Per Serving%Daily Value
Manganese 10 mg 500%

Other Ingredients: Potato Starch, Gelatin, Purified Water, Magnesium Stearate, Silica, MCT.

Directions: Take one capsule daily.

Well tolerated by most highly allergic individuals. No tablet binders, coatings or colorings. Free of the most common allergens such as corn, soy, yeast, barley, wheat, lactose (milk sugar) and all milk, citrus, fish and egg products. No added flavorings, sugars, salt, artificial sweeteners, colorings, preservatives or salicylates.

Additional Information

Additional Info

Suggested Use: 

Take one capsule daily.

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