Source Naturals Progesterone Cream (2 oz)

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Source Naturals Natural Progesterone Cream features natural progesterone USP from soy.
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Source Naturals Natural Progesterone Cream features natural progesterone USP from soy. This Progesterone Cream is guaranteed to contain 500 mg of progesterone per ounce and 22 mg per 1/4 teaspoon.

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Health Notes

Disclaimer: The following content is provided by Aisle7 and is for informational purposes only. It is based on scientific studies, clinical experience, or usage as cited in each article. Hi-Health provides this information as a service but does not endorse it. In addition, Aisle7 does not recommend or endorse any specific products.

Progesterone

Progesterone
This nutrient has been used in connection with the following health goals
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Menopause
Dose: Apply enough topical cream to provide 20 mg of the supplement to the skin daily
Progesterone, either natural or synthetic, has been linked to improved hot flashes, anxiety, depression, sleep problems, and sexual functioning, and quality of life. (more)
Amenorrhea
Dose: Consult a qualified healthcare practitioner
The oral, micronized form has been shown to successfully induce normal menstrual bleeding in women with secondary amenorrhea. (Use of this natural hormone should always be supervised by a doctor.) (more)
Dysmenorrhea
Dose: Refer to label instructions
Some practitioners report success using topical progesterone cream for dysmenorrhea. (more)
Premenstrual Syndrome
Dose: Refer to label instructions
Anecdotal reports suggest that progesterone may be effective against PMS symptoms. (more)
Menopause
Dose: Apply enough topical cream to provide 20 mg of the supplement to the skin daily
Progesterone, either natural or synthetic, has been linked to improved hot flashes, anxiety, depression, sleep problems, and sexual functioning, and quality of life. (more)
Osteoporosis
Dose: Consult a qualified healthcare practitioner
Preliminary evidence suggests that progesterone might reduce osteoporosis risk by promoting bone density. (more)
Amenorrhea
Dose: Consult a qualified healthcare practitioner
The oral, micronized form has been shown to successfully induce normal menstrual bleeding in women with secondary amenorrhea. (Use of this natural hormone should always be supervised by a doctor.) (more)
Dysmenorrhea
Dose: Refer to label instructions
Some practitioners report success using topical progesterone cream for dysmenorrhea. (more)
Premenstrual Syndrome
Dose: Refer to label instructions
Anecdotal reports suggest that progesterone may be effective against PMS symptoms. (more)
Menopause
Dose: Apply enough topical cream to provide 20 mg of the supplement to the skin daily  

Natural progesterone supplementation has been anecdotally linked to reduction in symptoms of menopause.1, 2, 3 In one trial, natural progesterone was found to have no independent effect on symptoms, and synthetic progestins were found to increase breast tenderness.4 However, a double-blind trial found that topical administration of natural progesterone cream led to a reduction in hot flashes in 83% of women, compared with improvement in only 19% of those given placebo.5 Preliminary research has found that oral, micronized progesterone therapy is associated with improved quality of life among postmenopausal women. However, oral micronized progesterone is available only by prescription in the United States.6 Hot flashes, anxiety, depression, sleep problems, and sexual functioning were among the symptoms improved in a majority of women surveyed. Synthetic progestins, also available only by prescription, have reduced symptoms of menopause.7, 8, 9

Progesterone is a hormone and, as such, concerns about its inappropriate use (i.e., as an over-the-counter supplement) have been raised. The amount of progesterone in commercially available creams varies widely, and the progesterone content is not listed on the label because the creams are legally regulated as cosmetics, not dietary supplements. Therefore, a physician should be consulted before using these hormone-containing creams as supplements. Although few side effects have been associated with topical progesterone creams, skin reactions may occur in some users. Effects of natural progesterone on breast cancer risk remain unclear; research has suggested both increased and reduced risk.

References

1. Lee JR. Natural Progesterone. The multiple roles of a remarkable hormone. Sebastipol, CA: BLL Publishing, 1993, 31-7.

2. Gaby AR. Commentary. Nutr Healing 1996;June:1,10-1.

3. Wright JV. Hormones for menopause. Nutr Healing 1996;June:1-2,9.

4. Greendale GA, Reboussin BA, Hogan P, et al. Symptom relief and side effects of postmenopausal hormones: results from the Postmenopausal Estrogen/Progestin Interventions Trial. Obstet Gynecol 1998;92:982-8.

5. Leonetti HB, Long S, Anasti JM. Transdermal progesterone cream for vasomotor symptoms and postmenopausal bone loss. Obstet Gynecol 1999;94:225-8.

6. Fitzpatrick LA, Pace C, Wiita B. Comparison of regimens containing oral micronized progesterone or medroxyprogesterone acetate on quality of life in postmenopausal women: a cross-sectional survey. J Women's Health Gender-Based Med 2000;9:381-7.

7. Bullock JL, Massey FM, Gambrell RD Jr. Use of medroxyprogesterone acetate to prevent menopausal symptoms. Obstet Gynecol 1975;46:165-8.

8. Morrison JC, Martin DC, Blair RA, et al. The use of medroxyprogesterone acetate for relief of climateric symptoms. Am J Obstet Gynecol 1980 138:99-104.

9. Schiff I, Tulchinsky D, Cramer D, Ryan KJ. Oral medroxyprogesterone in the treatment of postmenopausal symptoms. JAMA 1980;244:1443-5.

Amenorrhea
Dose: Consult a qualified healthcare practitioner  

Oral, micronized progesterone (200 to300 mg per day) has been shown in at least one double-blind trial to successfully induce normal menstrual bleeding in women with secondary amenorrhea.1 Use of this natural hormone should always be supervised by a doctor.

References

1. Shangold MM, Tomai TP, Cook JD, et al. Factors associated with withdrawal bleeding after administration of oral micronized progesterone in women with secondary amenorrhea. Fertil Steril 1991;56:1040-7.

Dysmenorrhea
Dose: Refer to label instructions  

Some practitioners report success using topical progesterone cream for dysmenorrhea.1 To date, this approach lacks sufficient research.

References

1. Hudson T. Natural progesterone: Clinical indications in women's health. Townsend Letter for Doctors and Patients 1999;Dec:140-3.

Premenstrual Syndrome
Dose: Refer to label instructions

Most well-controlled trials have not found vaginally applied natural progesterone to be effective against the symptoms of premenstrual syndrome.1 Only anecdotal reports have claimed that orally or rectally administered progesterone may be effective.2 Progesterone is a hormone, and as such, there are concerns about its inappropriate use. A physician should be consulted before using this or other hormones. Few side effects have been associated with use of topical progesterone creams, but skin reactions may occur. The effect of natural progesterone on breast cancer risk remains unclear; some research suggests the possibility of increased risk, whereas other research points to a possible reduction in risk.

References

1. Freeman E, Rickels K, Sondheimer SJ, Polansky M. Ineffectiveness of progesterone suppository treatment for premenstrual syndrome. JAMA 1990;264:349-53.

2. Martorano JT, Ahlgrimm M, Colbert T. Differentiating between natural progesterone and synthetic progestins: clinical implications for premenstrual syndrome and perimenopause management. Comp Ther 1998;24:336-9.

Menopause
Dose: Apply enough topical cream to provide 20 mg of the supplement to the skin daily  

Natural progesterone supplementation has been anecdotally linked to reduction in symptoms of menopause.1, 2, 3 In one trial, natural progesterone was found to have no independent effect on symptoms, and synthetic progestins were found to increase breast tenderness.4 However, a double-blind trial found that topical administration of natural progesterone cream led to a reduction in hot flashes in 83% of women, compared with improvement in only 19% of those given placebo.5 Preliminary research has found that oral, micronized progesterone therapy is associated with improved quality of life among postmenopausal women. However, oral micronized progesterone is available only by prescription in the United States.6 Hot flashes, anxiety, depression, sleep problems, and sexual functioning were among the symptoms improved in a majority of women surveyed. Synthetic progestins, also available only by prescription, have reduced symptoms of menopause.7, 8, 9

Progesterone is a hormone and, as such, concerns about its inappropriate use (i.e., as an over-the-counter supplement) have been raised. The amount of progesterone in commercially available creams varies widely, and the progesterone content is not listed on the label because the creams are legally regulated as cosmetics, not dietary supplements. Therefore, a physician should be consulted before using these hormone-containing creams as supplements. Although few side effects have been associated with topical progesterone creams, skin reactions may occur in some users. Effects of natural progesterone on breast cancer risk remain unclear; research has suggested both increased and reduced risk.

References

1. Lee JR. Natural Progesterone. The multiple roles of a remarkable hormone. Sebastipol, CA: BLL Publishing, 1993, 31-7.

2. Gaby AR. Commentary. Nutr Healing 1996;June:1,10-1.

3. Wright JV. Hormones for menopause. Nutr Healing 1996;June:1-2,9.

4. Greendale GA, Reboussin BA, Hogan P, et al. Symptom relief and side effects of postmenopausal hormones: results from the Postmenopausal Estrogen/Progestin Interventions Trial. Obstet Gynecol 1998;92:982-8.

5. Leonetti HB, Long S, Anasti JM. Transdermal progesterone cream for vasomotor symptoms and postmenopausal bone loss. Obstet Gynecol 1999;94:225-8.

6. Fitzpatrick LA, Pace C, Wiita B. Comparison of regimens containing oral micronized progesterone or medroxyprogesterone acetate on quality of life in postmenopausal women: a cross-sectional survey. J Women's Health Gender-Based Med 2000;9:381-7.

7. Bullock JL, Massey FM, Gambrell RD Jr. Use of medroxyprogesterone acetate to prevent menopausal symptoms. Obstet Gynecol 1975;46:165-8.

8. Morrison JC, Martin DC, Blair RA, et al. The use of medroxyprogesterone acetate for relief of climateric symptoms. Am J Obstet Gynecol 1980 138:99-104.

9. Schiff I, Tulchinsky D, Cramer D, Ryan KJ. Oral medroxyprogesterone in the treatment of postmenopausal symptoms. JAMA 1980;244:1443-5.

Osteoporosis
Dose: Consult a qualified healthcare practitioner Preliminary evidence suggests that progesterone might reduce the risk of osteoporosis.1 A preliminary trial using topically applied natural progesterone cream in combination with dietary changes, exercise, vitamin and calcium supplementation, and estrogen therapy reported large gains in bone density over a three-year period in a small group of postmenopausal women, but no comparison was made to examine the effect of using the same protocol without progesterone.2 Other trials have reported that adding natural progesterone to estrogen therapy did not improve the bone-sparing effects of estrogen and that progesterone applied topically every day for a year did not reduce bone loss.34 In a more recent double-blind study, however, progesterone had a modest bone-sparing effect in post-menopausal women.5
References

1. Prior JC. Progesterone as a bone-trophic hormone. Endocr Rev 1990;11:386-98.

2. Lee JR. Osteoporosis reversal: the role of progesterone. Int Clin Nutr Rev 1990;10:384-91.

3. Riis BJ, Thomsen K, Strom V, Christiansen C. The effect of percutaneous estradiol and natural progesterone on postmenopausal bone loss. Am J Obstet Gynecol 1987;156:61-5.

4. Leonetti HB, Long S, Anasti JM. Transdermal progesterone cream for vasomotor symptoms and postmenopausal bone loss. Obstet Gynecol 1999;94:225-8.

5. Lydeking-Olsen E, Beck-Jensen JE, Setchell KD, Holm-Jensen T. Soymilk or progesterone for prevention of bone loss: a 2 year randomized, placebo-controlled trial. Eur J Nutr 2004;43:246-57.

Amenorrhea
Dose: Consult a qualified healthcare practitioner  

Oral, micronized progesterone (200 to300 mg per day) has been shown in at least one double-blind trial to successfully induce normal menstrual bleeding in women with secondary amenorrhea.1 Use of this natural hormone should always be supervised by a doctor.

References

1. Shangold MM, Tomai TP, Cook JD, et al. Factors associated with withdrawal bleeding after administration of oral micronized progesterone in women with secondary amenorrhea. Fertil Steril 1991;56:1040-7.

Dysmenorrhea
Dose: Refer to label instructions  

Some practitioners report success using topical progesterone cream for dysmenorrhea.1 To date, this approach lacks sufficient research.

References

1. Hudson T. Natural progesterone: Clinical indications in women's health. Townsend Letter for Doctors and Patients 1999;Dec:140-3.

Premenstrual Syndrome
Dose: Refer to label instructions

Most well-controlled trials have not found vaginally applied natural progesterone to be effective against the symptoms of premenstrual syndrome.1 Only anecdotal reports have claimed that orally or rectally administered progesterone may be effective.2 Progesterone is a hormone, and as such, there are concerns about its inappropriate use. A physician should be consulted before using this or other hormones. Few side effects have been associated with use of topical progesterone creams, but skin reactions may occur. The effect of natural progesterone on breast cancer risk remains unclear; some research suggests the possibility of increased risk, whereas other research points to a possible reduction in risk.

References

1. Freeman E, Rickels K, Sondheimer SJ, Polansky M. Ineffectiveness of progesterone suppository treatment for premenstrual syndrome. JAMA 1990;264:349-53.

2. Martorano JT, Ahlgrimm M, Colbert T. Differentiating between natural progesterone and synthetic progestins: clinical implications for premenstrual syndrome and perimenopause management. Comp Ther 1998;24:336-9.

Progesterone is a hormone from a corpus luteum, formed by the cyclical rupture of an ovarian follicle. Progesterone is necessary for proper uterine and breast development and function.

Copyright © 2017 Healthnotes, Inc. All rights reserved. www.healthnotes.com

Learn more about Healthnotes, the company.

The information presented by Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2017.

Supplemental Facts

Ingredients


Deionized Water, Aloe Vera Leaf Gel, Cetearyl Glucoside, Caprylic/Capric Triglyceride, Cetyl Alcohol, Glycerin, Natural Progesterone USP from soy (500 mg per ounce), Wild Yam Root Extract, Tocopheryl Acetate (Natural Vitamin E), Lecithin Phospholipid, Glyceryl Stearate & PEG-100 Stearate, Jojoba Seed Oil, Squalene, Benzyl Alcohol, Phenoxyethanol, Stearic Acid, Grapefruit Seed Extract, Ginseng Seed Extract, Ginseng Root Extract, Sorbic Acid, Xanthan Gum, and Rosemary Oil.

Key Ingredients:

Aloe Vera Ginseng Sage
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