Solgar Glycine 500 mg (100 veggie caps)

Shop all Solgar SKU# 5236 Weight: 1.0 lb

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Glycine is a non-essential amino acid that is synthesized by the body and is used to form protein. It is a naturally sweet-tasting amino acid. This formulation provides Free Form L-Glycine to promote optimal absorption and assimilation.
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Glycine is a non-essential amino acid that is synthesized by the body and is used to form protein. It is a naturally sweet-tasting amino acid. This formulation provides Free Form L-Glycine to promote optimal absorption and assimilation.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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Health Notes

Disclaimer: The following content is provided by Aisle7 and is for informational purposes only. It is based on scientific studies, clinical experience, or usage as cited in each article. Hi-Health provides this information as a service but does not endorse it. In addition, Aisle7 does not recommend or endorse any specific products.

Glycine

Glycine
This nutrient has been used in connection with the following health goals
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Schizophrenia
Dose: 0.8 grams for every 2.2 lbs (1 kg) of body weight under medical supervision
Supplementing with glycine appears to help improve depression and mental symptoms and may reduce symptoms in people unresponsive to drug therapy. (more)
Schizophrenia
Dose: 0.8 grams for every 2.2 lbs (1 kg) of body weight under medical supervision  

There have been several reports of glycine reducing the symptoms of people with schizophrenia who were unresponsive to drug therapy.1 Large amounts of glycine (0.8 gram per 2.2 pounds of body weight per day) have been shown to reduce negative symptoms of schizophrenia and improve psychiatric rating scores in one preliminary trial;2 however, these results have not been repeated in later trials using similar (very high) amounts.3, 4 Earlier double-blind trials found significant improvements in depression and mental symptoms in people with schizophrenia who took glycine for six weeks.5, 6 Most trials demonstrated a moderate improvement in schizophrenia symptoms in those taking glycine supplements.7 Long-term supplementation with high amounts of glycine may be toxic to nerve tissue, however. Some preliminary successes have been reported using smaller amounts of glycine, such as 10 grams per day.8 Long-term studies on the safety of glycine therapy are needed.

References

1. Waziri R. Glycine therapy of schizophrenia: Some caveats. Biol Psychiatry 1996;39:155-6.

2. Heresco-Levy U, Javitt DC, Ermilov M, et al. Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia. Arch Gen Psychiatry 1999;56:29-36.

3. Evins AE, Fitzgerald SM, Wine L, et al. Placebo-controlled trial of glycine added to clozapine in schizophrenia. Am J Psychiatry 2000;157:826-8.

4. Potkin SG, Jin Y, Bunney BG, et al. Effect of clozapine and adjunctive high-dose glycine in treatment-resistant schizophrenia. Am J Psychiatry 1999;156:145-7.

5. Heresco-Levy U, Javitt DC, Ermilov M, et al. Double-blind, placebo-controlled, crossover trial of glycine adjuvant therapy for treatment-resistant schizophrenia. Br J Psychiatry 1996;169:610-7.

6. Javitt DC, Zylberman I, Zukin SR, et al. Amelioration of negative symptoms in schizophrenia by glycine. Am J Psychiatry 1994;151:1234-6.

7. Semba J. [Glycine therapy of schizophrenia; its rationale and a review of clinical trials]. Nihon Shinkei Seishin Yakurigaku Zasshi 1998;18:71-80 [review] [in Japanese].

8. Rosse RB, Theut SK, Banay-Schwartz M, et al. Glycine adjuvant therapy to conventional neuroleptic treatment in schizophrenia: an open-label, pilot study. Clin Neuropharmacol 1989;12:416-24.

Glycine is a nonessential amino acid used by the body to build proteins. It is present in considerable amounts in prostate fluid.

Copyright © 2017 Healthnotes, Inc. All rights reserved. www.healthnotes.com

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The information presented by Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2017.

Supplemental Facts

Ingredients

Supplement Facts

Serving Size: 1 Vegetable Capsule

Amount Per Serving

 

 

Glycine (Free From)

500 mg**

**Daily Value not established

Other Ingredients: Vegetable Cellulose, Microcrystalline cellulose, Vegetable Magnesium Stearate, Vegetable Stearic Acid.

FREE OF: Gluten, Wheat, Dairy, Soy, Yeast, Sugar, Sodium, Artificial Flavor, Sweetener, Preservatives and Color.

Additional Information

Additional Info

SUGGESTED USE: As a dietary supplement for adults, take one (1) to two (2) vegetable capsules daily, between meals, or as directed by a healthcare practitioner.

If you are pregnant, nursing, taking any medication or have a medical condition, please consult your healthcare practitioner before taking any dietary supplement. Keep out of reach of children. Store in a cool, dry place. Do not use if outer bottle seal is missing, torn or damaged in any way.

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