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Glucomannan, a type of water-soluble dietary fiber, may reduce many risk factors in people with IRS. A double-blind trial found that 8–13 grams per day of glucomannan significantly improved several measures of blood cholesterol control and one measure of blood glucose control in people with IRS.1 Another double-blind study of healthy people found that 30 grams per day of guar gum, a fiber similar to glucomannan, improved insulin sensitivity and many other components of IRS, including blood pressure and blood glucose, cholesterol, and triglycerides, leading the authors to recommend guar gum for people with IRS.2 However, in another study, obese people taking 8–16 grams per day of guar gum for 6–12 weeks did not experience any change in insulin sensitivity.3
1. Vuksan V, Sievenpiper JL, Owen R, et al. Beneficial effects of viscous dietary fiber from Konjac-mannan in subjects with the insulin resistance syndrome: results of a controlled metabolic trial. Diabetes Care 2000;23:9-14.
2. Landin K, Holm G, Tengborn L, Smith U. Guar gum improves insulin sensitivity, blood lipids, blood pressure, and fibrinolysis in healthy men. Am J Clin Nutr 1992;56:1061-5.
3. Cavallo-Perin P, Bruno A, Nuccio P, et al. Dietary guar gum supplementation does not modify insulin resistance in gross obesity. Acta Diabetol Lat 1985;22:139-142.
1. Doi K. Effect of konjac fibre (glucomannan) on glucose and lipids. Eur J Clin Nutr 1995;49(Suppl. 3):S190-7 [review].
2. Melga P, Giusto M, Ciuchi E, et al. Dietary fiber in the dietetic therapy of diabetes mellitus. Experimental data with purified glucomannans. Riv Eur Sci Med Farmacol 1992;14:367-73 [in Italian].
3. Huang CY, Zhang MY, Peng SS, et al. Effect of Konjac food on blood glucose level in patients with diabetes. Biomed Environ Sci 1990;3:123-31.
4. Vuksan V, Jenkins DJ, Spadafora P, et al. Konjac-mannan (glucomannan) improves glycemia and other associated risk factors for coronary heart disease in type 2 diabetes. A randomized controlled metabolic trial. Diabetes Care 1999;22:913-9.
5. Vorster HH, Lotter AP, Odendaal I, et al. Benefits from supplementation of the current recommended diabetic diet with gel fibre. Int Clin Nutr Rev 1988;8:140-6.
6. Cesa F, Mariani S, Fava A, et al. The use of vegetable fibers in the treatment of pregnancy diabetes and/or excessive weight gain during pregnancy. Minerva Ginecol 1990;42:271-4 [in Italian].
Glucomannan is a water-soluble dietary fiber that is derived from konjac root (Amorphophallus konjac). In a preliminary trial,1 addition of either 2.6 or 5.2 grams of glucomannan to a meal prevented hypoglycemia in adults with previous stomach surgery. A trial of glucomannan in children with hypoglycemia due to a condition known as “dumping syndrome” produced inconsistent results.2
1. Hopman WP, Houben PG, Speth PA, Lamers CB. Glucomannan prevents postprandial hypoglycaemia in patients with previous gastric surgery. Gut 1988;29:930-4.
2. Kneepkens CM, Fernandes J, Vonk RJ. Dumping syndrome in children. Diagnosis and effect of glucomannan on glucose tolerance and absorption. Acta Paediatr Scand 1988;77:279-86.
1. Vuksan V, Jenkins DJ, Spadafora P, et al. Konjac-mannan (glucomannan) improves glycemia and other associated risk factors for coronary heart disease in type 2 diabetes. A randomized controlled metabolic trial. Diabetes Care 1999;22:913-9.
2. Zhang MY, Huang CY, Wang X, et al. The effect of foods containing refined Konjac meal on human lipid metabolism. Biomed Environ Sci 1990;3:99-105.
3. Arvill A, Bodin L. Effect of short-term ingestion of konjac glucomannan on serum cholesterol in healthy men. Am J Clin Nutr 1995;61:585-9.
4. Walsh DE, Yaghoubian V, Behforooz A. Effect of glucomannan on obese patients: a clinical study. Int J Obes 1984;8:289-93.
Glucomannan is a water-soluble dietary fiber that is derived from konjac root. Like other sources of fiber, such as psyllium and fenugreek, glucomannan is considered a bulk-forming laxative. A preliminary trial1 and several double-blind trials2, 3, 4, 5 have found glucomannan to be an effective treatment for constipation. The amount of glucomannan shown to be effective as a laxative is 3 to 4 grams per day. In constipated people, glucomannan and other bulk-forming laxatives generally help produce a bowel movement within 12 to 24 hours.
1. Passaretti S, Franzoni M, Comin U, et al. Action of glucomannans on complaints in patients affected with chronic constipation: a multicentric clinical evaluation. Ital J Gastroenterol 1991;23:421-5.
2. Marzio L, Del Bianco R, Donne M, et al. Mouth-to-cecum transit time in patients affected by chronic constipation: effect of glucomannan. Am J Gastroenterol 1989;84:888-91.
3. Marsicano LJ, Berrizbeitia ML, Mondelo A. Use of glucomannan dietary fiber in changes in intestinal habit. G E N 1995;49:7-14 [in Spanish].
4. Signorelli P, Croce P, Dede A. A clinical study of the use of a combination of glucomannan with lactulose in the constipation of pregnancy. Minerva Ginecol 1996;48:577-82 [in Italian].
5. Staianno A, Simeone D, Giudice ED, et al. Effect of the dietary fiber glucomannan on chronic constipation in neurologically impaired children. J Pediatr 2000;136:41-5.
Glucomannan is a water-soluble dietary fiber that is derived from konjac root (Amorphophallus konjac). A preliminary clinical trial found that approximately one-third to one half of people with diverticular disease had reduced symptoms of diverticular disease after taking glucommanan.1 The amount of glucomannan shown to be effective as a laxative is 3–4 grams per day.
1. Biancardi G, Palmiero L, Ghirardi PE. Glucomannan in the treatment of overweight patients with osteoarthritis. Curr Ther Res 1989;46:908-12.
2. Vita PM, Restelli A, Caspani P, Klinger R. Chronic use of glucomannan in the dietary treatment of severe obesity. Minerva Med 1992;83:135-9 [in Italian].
3. Walsh DE, Yaghoubian V, Behforooz A. Effect of glucomannan on obese patients: a clinical study. Int J Obes 1984;8:289-93.
4. Livieri C, Novazi F, Lorini R. The use of highly purified glucomannan-based fibers in childhood obesity. Pediatr Med Chir 1992;14:195-8 [in Italian].
Increased fiber intake is thought to have potential benefit in a weight-loss program since dietary fiber dilutes calories, slows down the eating process, and may make people feel more full despite eating fewer calories.1 However, research on using fiber in the treatment of childhood obesity has focused on using fiber supplements rather than comparing low- and high-fiber diets. Supplementation for four months with 2 to 3 grams per day of a bulking agent called glucomannan, was effective in a group of obese adolescents in one controlled trial,2 but another controlled trial found no significant effect of 2 grams per day for two months.3
1. Kimm SY. The role of dietary fiber in the development and treatment of childhood obesity. Pediatrics 1995;96:1010-4.
2. Livieri C, Novazi F, Lorini R. The use of highly purified glucomannan-based fibers in childhood obesity. Pediatr Med Chir 1992;14:195-8 [in Italian].
3. Vido L, Facchin P, Antonello I, et al. Childhood obesity treatment: double blinded trial on dietary fibres (glucomannan) versus placebo. Padiatr Padol 1993;28:133-6.
Glucomannan is a water-soluble dietary fiber that is derived from konjac root (Amorphophallus konjac). Like other forms of dietary fiber, glucomannan is considered a “bulk-forming laxative.” Glucomannan promotes a larger, bulkier stool that passes through the colon more easily and requires less pressure—and subsequently less straining—to expel.
Copyright © 2017 Healthnotes, Inc. All rights reserved. www.healthnotes.com
The information presented by Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2017.
|Supplement Facts |
Serving Size: 3 Vcaps
|Amount Per Serving||%DV|
|Total Carbohydrate||2 g||1%*|
|Dietary Fiber||2 g||7%*|
|Glucomannan (root)||1.99 g||**|
|*Daily Values are based on a 2,000 calorie diet. |
**Daily Value (DV) not established.