The fruit rind of the Garcinia plant is used to make medicine. This pumpkin shaped fruit is found in southeast Asia and central Africa. The extract from the rind is hydroxycitric acid (HCA) which has been shown to support weight management. Several studies have suggested that hydroxycitric acid plays an important role in the regulation of endogenous lipid biosynthesis (fat accumulation). It is hypothesized that this occurs through the inhibition of alpha-amylase and intestinal alpha-glucosidase, leading to a reduction in carbohydrate metabolism. Additional studies have also suggested that hydroxycitric acid may positively influence appetite reduction.
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